After completing medical training in Lima, Peru, Patricia Jumbo-Lucioni earned a PhD in Nutrition Sciences from the University of Alabama at Birmingham in 2009, specializing in the genetics of complex traits and mitochondrial physiology using Drosophila melanogaster as model system. She furthered her expertise in fly genetics and neurodevelopmental deficits during her postdoctoral training at Emory and Vanderbilt University. She joined Samford University in 2016. Her research explores the therapeutic potential of ACE inhibitors and microbiome-targeted interventions in mitigating behavioral deficits and metabolic dysfunction in a Drosophila melanogaster (fruit fly) model of aging and Alzheimer’s disease.
Degrees and Certifications
- MD, Universidad Peruana Cayetano Heredia
- PhD, nutrition sciences, University of Alabama at Birmingham
- Certificate of College Teaching, Vanderbilt University
Awards and Honors
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AACP Biological Section-Excellence in Teaching Award, American Association of Colleges of Pharmacy, 2023
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2022 Carl Storm Underrepresented Minority (CSURM) Fellowship, Gordon Research Conferences, 2022
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Abstract acceptance at the 2022 Angiotensin Gordon Research Conference, Gordon Research Conferences, 2022
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2022 Scholar Award, Samford University McWhorter School of Pharmacy
Publications
- Vecchie' D, Wolter JM, Perry J, Jumbo-Lucioni P, De Luca M. The Impact of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Metabolic Rate in Drosophila melanogaster. Int J Mol Sci. 2024 Sep 20;25(18). doi: 10.3390/ijms251810103. PubMed PMID: 39337588; PubMed Central PMCID: PMC11432024.
- Lynn Crismon M, West-Strum DS, Dowling-McClay K, Drame I, Hastings TJ, Jumbo-Lucioni P, Marwitz KK, Spence A, Farrell D, Walker R. The Report of the 2021-2022 AACP Research and Graduate Affairs Committee. Am J Pharm Educ. 2023 Jan;87(1):ajpe9454. doi: 10.5688/ajpe9454. Review. PubMed PMID: 36781185; PubMed Central PMCID: PMC10159606.
- Moano GW, Adunlin G, Boyd K, Jumbo-Lucioni P, Bolaji B, Asare M. Perspectives of Pharmacists on the Structure, Decision-Making, and Communication Practices of Multidisciplinary Cancer Teams in Alabama. Innov Pharm. 2022;13(1). doi: 10.24926/iip.v13i1.4298. eCollection 2022. PubMed PMID: 36304689; PubMed Central PMCID: PMC9598974.
- Hernandez AR, Hoffman JM, Hernandez CM, Cortes CJ, Jumbo-Lucioni P, Baxter MG, Esser KA, Liu AC, McMahon LL, Bizon JL, Burke SN, Buford TW, Carter CS. Reuniting the Body "Neck Up and Neck Down" to Understand Cognitive Aging: The Nexus of Geroscience and Neuroscience. J Gerontol A Biol Sci Med Sci. 2022 Jan 7;77(1):e1-e9. doi: 10.1093/gerona/glab215. PubMed PMID: 34309630; PubMed Central PMCID: PMC8751793.
- Smith CA, Smith H, Roberts L, Coward L, Gorman G, Verma A, Li Q, Buford TW, Carter CS, Jumbo-Lucioni P. Probiotic Releasing Angiotensin (1-7) in a Drosophila Model of Alzheimer's Disease Produces Sex-Specific Effects on Cognitive Function. J Alzheimers Dis. 2022;85(3):1205-1217. doi: 10.3233/JAD-
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- PubMed PMID: 34924372; PubMed Central PMCID: PMC9549527.
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- Thomas J, Smith H, Smith CA, Coward L, Gorman G, De Luca M, Jumbo-Lucioni P. The Angiotensin-Converting Enzyme Inhibitor Lisinopril Mitigates Memory and Motor Deficits in a Drosophila Model of Alzheimer's Disease. Pathophysiology. 2021 Jun 18;28(2):307-319. doi: 10.3390/pathophysiology28020020. PubMed PMID: 35366264; PubMed Central PMCID: PMC8830455.
- Sun Y, Baptista LC, Roberts LM, Jumbo-Lucioni P, McMahon LL, Buford TW, Carter CS. The Gut Microbiome as a Therapeutic Target for Cognitive Impairment. J Gerontol A Biol Sci Med Sci. 2020 Jun 18;75(7):1242-1250. doi: 10.1093/gerona/glz281. Review. PubMed PMID: 31811292; PubMed Central PMCID: PMC7302188.
- Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M. Age- and Genotype- Specific Effects of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Mitochondrial and Metabolic Parameters in Drosophila melanogaster. Int J Mol Sci. 2018 Oct 26;19(11). doi: 10.3390/ijms19113351. PubMed PMID: 30373167; PubMed Central PMCID: PMC6274988.
- See complete list of publications
Involvement
- Alabama Academy of Science, Member
- Alzheimer’s Association, Member.
- Alzheimer’s Association-Alabama Chapter, Community Educator
- American Association of Colleges of Pharmacy, Biological Sciences section member
Expertise
Metabolic and mitochondrial physiology, neurodegenerative diseases, Drosophila husbandry and genetics
Research Areas
- Pharmacological interventions in Alzheimer’s disease
- Behavioral and molecular characterization of neurodegenerative models
- Gut-brain axis as a therapeutic target for cognitive impairment
- Innovations in pharmacy education to enhance research engagement
